Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950092 | 0.90 | KCNQ3 (0.42) | KCNQ3KCNQ2KDM4ECRHBPCRHR2 | |
| SCHEMBL7230617 | 0.82 | HSP90AA1 (0.43) | KDM4EKMT2AKIF11MAOBB3GNT2 | |
| SCHEMBL14934065 | 0.81 | MAOB (0.38) | KDM4EMAOBB3GNT2 | |
| SCHEMBL319785 | 0.80 | DAO (0.52) | B3GNT2 | |
| SCHEMBL31709866 | 0.80 | AKT2 (0.44) | OPRM1B3GNT2 | |
| SCHEMBL7436018 | 0.79 | B3GNT2 (0.47) | KDM4EGAAKMT2AKIF11B3GNT2 | |
| SCHEMBL605123 | 0.79 | OPRM1 (0.54) | LIPEOPRM1GPR119 | |
| SCHEMBL2256797 | 0.76 | DAO (0.47) | KMT2A | |
| SCHEMBL28467050 | 0.76 | CA12 (0.45) | KDM4ECRHBPCRHR2GAAKMT2A | |
| SCHEMBL30327184 | 0.76 | CA12 (0.45) | KDM4ECRHBPCRHR2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076810-A1 | Benzoureas Having Anti-Diabetic Activity | MERCK SHARP & DOHME CORP. | 2008-03-27 | — | — | US | disclosed |
| US-20080076810-A1 | Benzoureas Having Anti-Diabetic Activity | MERCK SHARP & DOHME CORP. | 2008-03-27 | — | — | US | disclosed |
| US-20080076810-A1 | Benzoureas Having Anti-Diabetic Activity | MERCK SHARP & DOHME CORP. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076810-A1 | Benzoureas Having Anti-Diabetic Activity | PPARD, PPARG, GPR119 | KCNQ3 2625/4885KCNQ2 1714/4885KDM4E 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.