Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089649 | 1.00 | DPP4 (0.44) | DPP4LTA4HLPLLIPGCYP17A1 | |
| SCHEMBL1333578 | 0.89 | LTA4H (0.56) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL8571707 | 0.89 | LTA4H (0.56) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL1756468 | 0.89 | LTA4H (0.56) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL833843 | 0.89 | LTA4H (0.56) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL11957366 | 0.88 | PGR (0.40) | DPP4LTA4HCYP17A1KDM4EALDH1A1 | |
| SCHEMBL2769963 | 0.88 | DPP4 (0.57) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL14284941 | 0.88 | DPP4 (0.57) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL2028518 | 0.88 | DPP4 (0.57) | DPP4LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL4280934 | 0.88 | LTA4H (0.54) | DPP4LTA4HKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | SLC22A4, SLC19A2, SLC22A1 | DPP4 2060/4885LTA4H 1564/4885LPL 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.