SCHEMBL4949412

SCHEMBL4949412

Brc1cc(C(c2ccccc2)(C(Br)(Br)Br)C(Br)(Br)Br)c(Br)c(Br)c1Br

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653858 0.81 TDP1 (0.30) TDP1
SCHEMBL4810985 0.80 TDP1 (0.32) TDP1
SCHEMBL28392904 0.80 TDP1 (0.32) TDP1
SCHEMBL29446475 0.80 TDP1 (0.32) TDP1
SCHEMBL9780554 0.78 EIF2AK2 (0.32) TDP1
SCHEMBL8854109 0.78 KCNN4 (0.39) TDP1
SCHEMBL1226128 0.78
SCHEMBL4952593 0.78
SCHEMBL10881874 0.77 CYP2C19 (0.33) TDP1
SCHEMBL4948749 0.76 ALDH1A1 (0.31) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378449-B2 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION (US) 2008-05-27 US disclosed
US-20070093582-A1 POLY(BROMOARYL)ALKANE ADDITIVES AND METHODS FOR THEIR PREPARATION AND USE ALBEMARLE CORPORATION (US) 2007-04-26 US disclosed
US-7129385-B2 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION (US) 2006-10-31 US disclosed
US-20040195087-A1 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION 2004-10-07 US disclosed
US-6743825-B1 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION 2004-06-01 US disclosed