Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844611 | 0.82 | CES2 (0.67) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL30214744 | 0.81 | CES1 (0.65) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL2500212 | 0.81 | CES1 (0.65) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL6827745 | 0.80 | CES2 (0.74) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL63427 | 0.80 | CES2 (0.74) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL29351426 | 0.80 | CES2 (0.74) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL21509990 | 0.79 | PARP1 (0.64) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL1009355 | 0.78 | CA1 (0.61) | CES2CES1PARP1RAB9ANPSR1 | |
| SCHEMBL3823617 | 0.78 | CA1 (0.61) | CES2CES1PARP1RAB9ANPSR1 | |
| SCHEMBL10403563 | 0.78 | CES2 (0.71) | CES2CES1PARP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457487-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE CIS-PIPERIDINE DERIVATIVES | Toray Fine Chemicals Co., Ltd. (JP) | 2004-09-15 | — | — | EP | claimed |
| US-20040171836-A1 | Method for producing optical-active cis-piperidine derivatives | TORAY FINE CHEMICALS CO., LTD., A CORPORATION OF JAPAN, (JP) | 2004-09-02 | — | — | US | claimed |
| EP-4613747-A1 | METHOD FOR PREPARING FINERENONE BY MEANS OF RESOLVING RACEMATE WITH DIASTEREOMERIC TARTARIC ESTER | Nanjing Vcare Pharmatech Co., Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094181-A1 | METHOD FOR PREPARING FINERENONE BY MEANS OF RESOLVING RACEMATE WITH DIASTEREOMERIC TARTARIC ESTER | 南京威凯尔生物医药科技有限公司 | 2024-05-10 | — | — | WO | disclosed |
| US-7358384-B2 | Processes for the recovery of optically active diacyltartaric acids | TORAY FINE CHEMICALS CO., LTD. (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20060058546-A1 | Processes for the recovery of optically active diacyltartatic acids | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1586551-A1 | PROCESSES FOR THE RECOVERY OF OPTICALLY ACTIVE DIACYLTARTATIC ACIDS | Toray Fine Chemicals Co., Ltd. (JP) | 2005-10-19 | — | — | EP | disclosed |
| EP-1457487-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE CIS-PIPERIDINE DERIVATIVES | Toray Fine Chemicals Co., Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-20040171836-A1 | Method for producing optical-active cis-piperidine derivatives | TORAY FINE CHEMICALS CO., LTD., A CORPORATION OF JAPAN, (JP) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171836-A1 | Method for producing optical-active cis-piperidine derivatives | TYR, DDC, TARBP1 | CES2 1406/4885CES1 1028/4885PARP1 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.