SCHEMBL4949839

SCHEMBL4949839

NC(N)=NC(=O)c1ccc(-c2cccc(F)c2)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 19/20 1.00
NR4A1 P22736 1/20 0.65
NR4A2 P43354 1/20 0.65
NR4A3 Q92570 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4945617 0.87 SLC9A1 (1.00) SLC9A1
SCHEMBL4936901 0.84 SLC9A1 (0.73) SLC9A1
SCHEMBL6671019 0.84 NR4A1 (0.74) SLC9A1NR4A1NR4A2NR4A3
SCHEMBL4943804 0.83 SLC9A1 (1.00) SLC9A1
SCHEMBL4936813 0.83 SLC9A1 (1.00) SLC9A1
SCHEMBL4943707 0.82 SLC9A1 (1.00) SLC9A1
SCHEMBL3050183 0.79 NR4A1 (1.00) SLC9A1NR4A1NR4A2NR4A3
SCHEMBL4941162 0.79 MAPT (0.66) SLC9A1
SCHEMBL4943946 0.78 SLC9A1 (0.72) SLC9A1
SCHEMBL13078324 0.78 NR4A1 (0.74) SLC9A1NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7351843-B2 Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-04-01 US claimed
US-20070299131-A1 Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2007-12-27 US claimed
US-7351843-B2 Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-04-01 US disclosed
US-20070299131-A1 Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299131-A1 Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them SLC9A1, NHERF1, SLC5A1 SLC9A1 1/4885NR4A1 4396/4885NR4A2 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.