Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802829 | 0.84 | CA12 (0.75) | RAB9AALDH1A1LMNAKMT2ALTA4H | |
| SCHEMBL4888845 | 0.84 | CDK5 (0.61) | RAB9AALDH1A1LMNAKMT2ACA2 | |
| SCHEMBL320807 | 0.83 | HPGD (0.68) | RAB9AALDH1A1LMNAKMT2AEPHX2 | |
| SCHEMBL4949674 | 0.82 | CA12 (0.60) | RAB9AALDH1A1LMNAKMT2ALTA4H | |
| SCHEMBL8803541 | 0.81 | LTA4H (0.79) | RAB9AALDH1A1KMT2ALTA4HEPHX2 | |
| SCHEMBL30941107 | 0.79 | NPC1 (0.62) | RAB9AALDH1A1LMNAKMT2ALTA4H | |
| SCHEMBL1259379 | 0.79 | RAB9A (0.58) | RAB9AALDH1A1LMNAKMT2ALTA4H | |
| SCHEMBL23607918 | 0.79 | KDM4E (0.59) | RAB9AALDH1A1LMNAKMT2ACA12 | |
| SCHEMBL28992212 | 0.77 | ALDH1A1 (1.00) | RAB9AALDH1A1LMNAKMT2ACA12 | |
| SCHEMBL5861356 | 0.77 | ALDH1A1 (1.00) | RAB9AALDH1A1LMNAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083054-A2 | LIGANDS FOR CARDIAC BETA1 ADRENOCEPTOR FOR IMAGING CONGESTIVE HEART FAILURE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |