Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.50 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950018 | 0.81 | TDP1 (0.51) | SMN1; SMN2ALOX5APFEN1 | |
| SCHEMBL4950128 | 0.81 | GRIA2 (0.52) | GRIA2KCNH2ADAMTS4PIP4K2APIP4K2B | |
| SCHEMBL6513336 | 0.78 | MCOLN3 (0.55) | KDM1AALDH1A1SMN1; SMN2ALOX5APFEN1 | |
| SCHEMBL4951169 | 0.76 | GRIA4 (0.51) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4952483 | 0.75 | KDM1A (0.55) | GRIA2KCNH2KDM1A | |
| SCHEMBL3786463 | 0.75 | NQO2 (0.73) | CYP17A1CYP11B1CYP11B2NQO2MEN1 | |
| SCHEMBL1677246 | 0.74 | KDM1A (0.64) | GRIA2KCNH2KDM1A | |
| SCHEMBL8577619 | 0.73 | SMN1; SMN2 (0.70) | PIP4K2APIP4K2BCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL4374171 | 0.73 | ALOX5AP (0.52) | KDM1AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL12919978 | 0.73 | CYP17A1 (0.60) | GRIA2ADAMTS4PIP4K2APIP4K2BCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |