Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208097 | 0.87 | ABCB1 (0.43) | ALDH1A1TSHRABCB1MAPTSMN1; SMN2 | |
| SCHEMBL25925962 | 0.84 | PTPN1 (0.47) | GABRA1GABRB2ALDH1A1TSHRKMT2A | |
| SCHEMBL19565679 | 0.84 | HCRTR1 (0.44) | TSHRABCB1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2257068 | 0.82 | GABRA1 (0.52) | GABRA1GABRB2ALDH1A1TSHRMAPT | |
| SCHEMBL10454822 | 0.82 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1TSHRKMT2A | |
| SCHEMBL943719 | 0.82 | L3MBTL1 (0.45) | GABRA1GABRB2ALDH1A1TSHRABCB1 | |
| SCHEMBL30402144 | 0.82 | L3MBTL1 (0.45) | GABRA1GABRB2ALDH1A1TSHRABCB1 | |
| SCHEMBL10825064 | 0.82 | PDK2 (0.45) | ALDH1A1TSHRABCB1MAPTSMN1; SMN2 | |
| SCHEMBL8702465 | 0.81 | ALDH1A1 (0.50) | GABRA1GABRB2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL725761 | 0.81 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1TSHRABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254432-A2 | Method of preparing alpha-arylalkanoic esters | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1988-01-27 | — | — | EP | claimed |
| JP-57163337-A | — | — | None | — | — | JP | disclosed |
| WO-2008074717-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 2-ARYLPROPANOLS HAVING A PROFEN-LIKE SUBSTITUTED ARYL RESIDUE | ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA (IT) | 2008-06-26 | — | — | WO | disclosed |
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |
| EP-0424242-A2 | Process for preparing carboxylic acids by means of oxidation of corresponding aldehydes | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 1991-04-24 | — | — | EP | disclosed |
| EP-0254432-A2 | Method of preparing alpha-arylalkanoic esters | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0048136-B1 | PROCESS FOR PREPARING ALPHA-AROMATIC GROUP SUBSTITUTED ALKANOIC ACIDS OR ESTERS THEREOF | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1986-06-11 | — | — | EP | disclosed |
| JP-S57163337-A | PREPARATION OF PROPIONIC ACID DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1982-10-07 | — | — | JP | disclosed |