Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 11/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665677 | 0.85 | BCAT2 (0.51) | BCAT2KEAP1NFE2L2CCNE2CDK4 | |
| SCHEMBL4950617 | 0.75 | BCAT2 (0.54) | BCAT2PARP1DHODHCSNK1A1TYRO3 | |
| SCHEMBL4532599 | 0.75 | HNF4A (0.51) | BCAT2DHODH | |
| SCHEMBL3914170 | 0.75 | CSNK1A1 (0.44) | BCAT2KEAP1NFE2L2PARP1DHODH | |
| SCHEMBL2650295 | 0.73 | CSNK1A1 (0.54) | BCAT2KEAP1NFE2L2PARP1CSNK1A1 | |
| SCHEMBL11968815 | 0.71 | POLB (0.42) | DHODH | |
| SCHEMBL3914195 | 0.70 | BCAT2 (0.41) | BCAT2KEAP1NFE2L2CDK2PARP1 | |
| SCHEMBL196009 | 0.69 | — | — | |
| SCHEMBL6606176 | 0.69 | BCAT2 (0.55) | BCAT2KEAP1NFE2L2PARP1CSNK1A1 | |
| SCHEMBL6782270 | 0.69 | CCNE2 (0.41) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |