Iprindole

Iprindole

SCHEMBL49509

CN(C)CCCn1c2c(c3ccccc31)CCCCCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 1.00
CHRM2 P08172 1/20 1.00
HTR1A P08908 1/20 1.00
CHRM5 P08912 1/20 1.00
ADRA2A P08913 1/20 1.00
DRD2 P14416 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
CHRM3 P20309 1/20 1.00
DRD4 P21917 1/20 1.00
SLC6A2 P23975 1/20 1.00
HRH2 P25021 1/20 1.00
HTR2A P28223 1/20 1.00
HTR2C P28335 1/20 1.00
AVPR2 P30518 1/20 1.00
ADRA1A P35348 1/20 1.00
HRH1 P35367 1/20 1.00
DRD3 P35462 1/20 1.00
OPRK1 P41145 1/20 1.00
HTR2B P41595 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iprindole SCHEMBL29407410 1.00 HTR6 (1.00) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL11891460 1.00 HTR6 (1.00) HTR6CHRM2HTR1ACHRM5ADRA2A
Iprindole SCHEMBL5705755 0.99 HTR6 (0.97) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL25818911 0.92 HTR6 (0.85) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL11530278 0.86 CHRM2 (0.76) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL11531885 0.84 CHRM2 (0.72) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL10737829 0.82 HTR6 (0.70) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL10738401 0.82 HTR6 (0.70) HTR6CHRM2HTR1ACHRM5ADRA2A
SCHEMBL10735873 0.82 HRH3 (0.70) HTR6CHRM2HTR1ACHRM5ADRA2A
Melitracen SCHEMBL10002403 0.82 SLC6A2 (0.67) HTR6CHRM2HTR1ACHRM5ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4608 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034065-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION DOUGLAS PHARMACEUTICALS LTD (NZ) 2026-02-05 US claimed
US-20260001942-A1 TREATMENT OF HEADACHE DISORDERS AND/OR PSYCHIATRIC SYMPTOMS USING ANTI-CGRP ANTIBODIES, AND COMPOSITIONS AND METHODS RELATED THERETO H LUNDBECK AS (DK) 2026-01-01 US claimed
WO-2025262247-A1 TREATMENT OF HEADACHE DISORDERS AND/OR PSYCHIATRIC SYMPTOMS USING ANTI-CGRP ANTIBODIES, AND COMPOSITIONS AND METHODS RELATED THERETO H. LUNDBECK A/S (DK) 2025-12-26 WO claimed
US-12472146-B2 Extended release pharmaceutical formulation DOUGLAS PHARMACEUTICALS, LTD. (NZ) 2025-11-18 US claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
US-12350379-B2 Extended release pharmaceutical formulation and methods of treatment DOUGLAS PHARMACETICALS LTD (NZ) 2025-07-08 US claimed
US-12263178-B2 Pharmaceutical compositions and methods POP TEST ONCOLOGY LLC (US) 2025-04-01 US claimed
EP-3946296-B9 EXTENDED RELEASE PHARMACEUTICAL FORMULATION DOUGLAS PHARMACEUTICALS LTD (NZ) 2024-12-25 EP claimed
EP-4479032-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS Sage Therapeutics, Inc. (US) 2024-12-25 EP claimed
US-12128140-B2 Extended release pharmaceutical formulation DOUGLAS PHARMACEUTICALS, LTD. (NZ) 2024-10-29 US claimed
WO-2000064441-A2 COMPOUND FOR USE AS A MEDICAMENT FOR TREATMENT OF DISORDERS INVOLVING BRONCHOCONTRACTION RESPIRATORIUS AB (SE) 2000-11-02 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5922341-A Local administration of pharmacologically active agents to treat premature ejaculation VIVUS, INCORPORATED (US) 1999-07-13 US claimed
WO-1997041878-A1 TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
EP-0724450-A1 COMPOSITION FOR WEIGHT REDUCTION CONTAINING EPHEDRINE AND A MINERAL SALT OR CHELATE Keown, Wendy J. (US) 1996-08-07 EP claimed
US-5543405-A MIXTURE OF EPHEDRINE AND CHROMIUM PICOLINATE KEOWN WENDY J (US) 1996-08-06 US claimed
WO-1995011034-A1 COMPOSITION FOR WEIGHT REDUCTION CONTAINING EPHEDRINE AND A MINERAL SALT OR CHELATE KEOWN WENDY J (US) 1995-04-27 WO claimed
US-5256409-A Complexing two drug haptens to carrier protein THERAPEUTIC ANTIBODIES, INC. (US) 1993-10-26 US claimed
EP-0174342-B1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES UNIVERSITY OF FLORIDA (US) 1989-12-20 EP claimed
EP-0089948-B1 PHARMACEUTICAL COMPOSITIONS COPPEN, Alec James (GB) 1985-08-14 EP claimed