Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.85 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.85 |
| ▸ | HTR1A | P08908 | 1/20 | 0.85 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.85 |
| ▸ | DRD2 | P14416 | 1/20 | 0.85 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.85 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.85 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.85 |
| ▸ | DRD4 | P21917 | 1/20 | 0.85 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.85 |
| ▸ | HRH2 | P25021 | 1/20 | 0.85 |
| ▸ | HTR2A | P28223 | 1/20 | 0.85 |
| ▸ | HTR2C | P28335 | 1/20 | 0.85 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.85 |
| ▸ | HRH1 | P35367 | 1/20 | 0.85 |
| ▸ | DRD3 | P35462 | 1/20 | 0.85 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.85 |
| ▸ | HTR2B | P41595 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891460 | 0.92 | HTR6 (1.00) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| Iprindole SCHEMBL49509 | 0.92 | HTR6 (1.00) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| Iprindole SCHEMBL29407410 | 0.92 | HTR6 (1.00) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| Iprindole SCHEMBL5705755 | 0.91 | HTR6 (0.97) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| SCHEMBL11533022 | 0.85 | HTR6 (0.64) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| SCHEMBL11530224 | 0.83 | CHRM2 (0.61) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| SCHEMBL18457140 | 0.82 | CA1 (0.67) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| SCHEMBL24110461 | 0.81 | HRH1 (0.58) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| SCHEMBL24110646 | 0.81 | HTR6 (0.58) | HTR6CHRM2HTR1ACHRM5ADRA2A | |
| SCHEMBL14157802 | 0.80 | CA1 (0.71) | HTR6CHRM2HTR1ACHRM5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | HTR6 42/4885CHRM2 514/4885HTR1A 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.