Indoramin

Indoramin

SCHEMBL49517

O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 2/20 1.00
ADRA1A P35348 2/20 1.00
ADRA1B P35368 2/20 1.00
ADRA2A P08913 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
BCHE P06276 3/20 0.62
ACHE P22303 3/20 0.62
SIGMAR1 Q99720 1/20 0.60
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
CARM1 Q86X55 1/20 0.58
PRMT6 Q96LA8 1/20 0.58
HTR2A P28223 2/20 0.57
HPGD P15428 1/20 0.57
HTT P42858 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indoramin SCHEMBL29370437 1.00 ADRA1D (1.00) ADRA1DADRA1AADRA1BADRA2AADRA2B
Indoramin SCHEMBL123678 0.99 ADRA1D (0.98) ADRA1DADRA1AADRA1BADRA2AADRA2B
Indoramin SCHEMBL29801648 0.99 ADRA1D (0.98) ADRA1DADRA1AADRA1BADRA2AADRA2B
Indoramin SCHEMBL1651262 0.98 ADRA1D (0.96) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11303310 0.92 ADRA2A (0.85) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11506582 0.92 ADRA2A (0.85) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11545710 0.91 ADRA2A (0.83) ADRA1DADRA1AADRA1BADRA2AADRA2B
Hydrochloric Acid SCHEMBL11545694 0.91 ADRA2A (0.83) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11070428 0.90 ADRA2A (0.81) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL10783732 0.89 ADRA2A (0.80) ADRA1DADRA1AADRA1BADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6530 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
US-12472158-B2 Methods of treating trigeminal nerve pain VANDERBILT UNIVERSITY (US) 2025-11-18 US claimed
US-20250268841-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2025-08-28 US claimed
US-20250222008-A1 EYEDROPS CONTAINING AN ALPHA1-BLOCKER FOR INHIBITING MYOPIA PROGRESSION TSUBOTA LABORATORY, INC. (JP) 2025-07-10 US claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US claimed
US-20250120907-A1 Transmucosal Drug Delivery System Masiz, John J. (US) 2025-04-17 US claimed
US-12246098-B2 Trans-epithelial membrane drug delivery system BioPhysics Pharma, Inc. (US) 2025-03-11 US claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP claimed
CN-119303086-A Pharmaceutical composition for treating autism 斯塔利克拉股份有限公司 2025-01-14 CN claimed
EP-0193427-A1 Warhead with shaped charges arranged in tandem ETAT-FRANCAIS représenté par le DELEGUE GENERAL POUR L'ARMEMENT (DPAG) (FR) 1986-09-03 EP claimed
US-4607042-A 3-(2-(4-BENZAMIDO-1-PIPERIDYL)ETHYL)INDOLE JOHN WYETH & BROTHER LTD. (GB) 1986-08-19 US claimed
EP-0067539-B1 SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION JOHN WYETH & BROTHER LIMITED (GB) 1985-09-18 EP claimed
EP-0154553-A2 Use of compounds for increasing plasma high density lipoprotein cholesterol JOHN WYETH & BROTHER LIMITED (GB) 1985-09-11 EP claimed
US-4524060-A PELLET MIXTURE OF INDORAMIN, CELLULOSE, AND WETTING AGENT IN GASTRIC JUICE PERMEABLE COATINGS JOHN WYETH & BROTHER LIMITED (GB) 1985-06-18 US claimed
US-4428954-A CHARACTERIZED BY POOR OXYGENATION JOHN WYETH AND BROTHER LIMITED (GB) 1984-01-31 US claimed
EP-0067539-A2 Sustained release pharmaceutical composition JOHN WYETH & BROTHER LIMITED (GB) 1982-12-22 EP claimed
US-4223008-A HYPOTENSIVE JOHN WYETH & BROTHER LIMITED (GB) 1980-09-16 US claimed
US-4162252-A Process for preparing 3-[(benzamidopiperid-1-yl)alkyl] indoles JOHN WYETH & BROTHER LIMITED (GB) 1979-07-24 US claimed
US-4140691-A Process for preparing 3-[2-(4-benzamidopiperid-1-yl)ethyl]indole JOHN WYETH & BROTHER, LTD. (GB) 1979-02-20 US claimed