Indoramin

Indoramin

SCHEMBL29370437

O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 2/20 1.00
ADRA1A P35348 2/20 1.00
ADRA1B P35368 2/20 1.00
ADRA2A P08913 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
BCHE P06276 3/20 0.62
ACHE P22303 3/20 0.62
SIGMAR1 Q99720 1/20 0.60
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
CARM1 Q86X55 1/20 0.58
PRMT6 Q96LA8 1/20 0.58
HTR2A P28223 2/20 0.57
HPGD P15428 1/20 0.57
HTT P42858 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indoramin SCHEMBL49517 1.00 ADRA1D (1.00) ADRA1DADRA1AADRA1BADRA2AADRA2B
Indoramin SCHEMBL123678 0.99 ADRA1D (0.98) ADRA1DADRA1AADRA1BADRA2AADRA2B
Indoramin SCHEMBL29801648 0.99 ADRA1D (0.98) ADRA1DADRA1AADRA1BADRA2AADRA2B
Indoramin SCHEMBL1651262 0.98 ADRA1D (0.96) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11303310 0.92 ADRA2A (0.85) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11506582 0.92 ADRA2A (0.85) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11545710 0.91 ADRA2A (0.83) ADRA1DADRA1AADRA1BADRA2AADRA2B
Hydrochloric Acid SCHEMBL11545694 0.91 ADRA2A (0.83) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL11070428 0.90 ADRA2A (0.81) ADRA1DADRA1AADRA1BADRA2AADRA2B
SCHEMBL10783732 0.89 ADRA2A (0.80) ADRA1DADRA1AADRA1BADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4403176-A2 TOPICAL PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ANAL FISSURES AND HEMORRHOIDS Ferring B.V. (NL) 2024-07-24 EP claimed
US-20240165089-A1 METHOD FOR TREATING MYOPIA WITH VINPOCETINE Eye Hospital, Wenzhou Medical University (CN) 2024-05-23 US claimed
EP-3498297-B1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM STALICLA S A (CH) 2023-06-21 EP claimed
CN-115003278-A Topical composition and method for determining cooling capacity of composition 未来医疗发展有限公司 2022-09-02 CN claimed
US-20220151918-A1 TOPICAL PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ANAL FISSURES AND HEMORRHOIDS FERRING B.V. (NL) 2022-05-19 US claimed
EP-3220942-B1 COMPOSITIONS COMPRISING LOW DOSE DESMOPRESSIN IN COMBINATION WITH AN ALPHA-ADRENERGIC RECEPTOR ANTAGONIST SERENITY PHARMACEUTICALS LLC (US) 2022-04-27 EP claimed
US-20220034911-A1 METHOD OF MITIGATION OF DEATH FROM EPILEPTIC SEIZURES VEGA JOSE (US) 2022-02-03 US claimed
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed
US-20250276066-A1 METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS GERO PTE LTD (SG) 2025-09-04 US disclosed
WO-2025124483-A1 ORAL DRUG DOSAGE FORM FOR TARGETED DRUG DELIVERY BASED ON TRACKING MARKER AND METHODS OF DESIGN AND USE THEREOF Triastek, Inc. (CN) 2025-06-19 WO disclosed
US-20250064781-A1 METHODS OF TREATING, AMELIORATING, AND/OR PREVENTING STRESS-RELATED DISORDER UNIV YALE (US) 2025-02-27 US disclosed
US-20250041211-A1 OPHTHALMIC PREPARATION AND APPLICATION THEREOF IN TREATMENT OF PRESBYOPIA Eye Hospital, Wenzhou Medical University (CN) 2025-02-06 US disclosed
CN-119303086-A Pharmaceutical composition for treating autism 斯塔利克拉股份有限公司 2025-01-14 CN disclosed
US-20220151918-A1 TOPICAL PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ANAL FISSURES AND HEMORRHOIDS FERRING B.V. (NL) 2022-05-19 US disclosed
CN-114470207-A Compositions and methods relating to treatment of pulmonary hypertension 布里格姆及妇女医院股份有限公司 2022-05-13 CN disclosed
CN-109431965-B Pharmaceutical dosage forms and uses thereof 南京三迭纪医药科技有限公司 2022-04-08 CN disclosed
CN-114225119-A Expandable balloon comprising a coating 祥丰医疗私人有限公司 2022-03-25 CN disclosed
CN-114173793-A Composition, kit and use thereof 泰瑞威公司 2022-03-11 CN disclosed
CN-114080220-A Method for preparing gel-forming composition 泰瑞威公司 2022-02-22 CN disclosed
US-20220034911-A1 METHOD OF MITIGATION OF DEATH FROM EPILEPTIC SEIZURES VEGA JOSE (US) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165089-A1 METHOD FOR TREATING MYOPIA WITH VINPOCETINE MYOC, VAMP7, MYOF ADRA1D 2899/4885ADRA1A 1692/4885ADRA1B 1935/4885
US-20250276066-A1 METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS UPF1, NLN, BRCA1 ADRA1D 3567/4885ADRA1A 3325/4885ADRA1B 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.