Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 5/20 | 0.39 |
| ▸ | HPGDS | O60760 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381749 | 0.87 | TBK1 (0.45) | FASNHPGDSGSK3BUSP30HRH3 | |
| SCHEMBL4378670 | 0.81 | TBK1 (0.50) | FASNHPGDSUSP30HDAC2HRH3 | |
| SCHEMBL4381747 | 0.80 | KMT2A (0.40) | GSK3BCYP2D6 | |
| SCHEMBL4378741 | 0.80 | ALDH1A1 (0.44) | GSK3BALDH1A1CYP2D6 | |
| SCHEMBL2066076 | 0.79 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL4377805 | 0.78 | ALDH1A1 (0.45) | GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL4383564 | 0.77 | SCN9A (0.42) | HPGDSGSK3B | |
| SCHEMBL4768777 | 0.76 | GSK3B (0.38) | GSK3BCYP2D6 | |
| SCHEMBL2065426 | 0.76 | DRD4 (0.42) | GSK3B | |
| SCHEMBL4389917 | 0.75 | HPGDS (0.39) | HPGDSGSK3BALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939187-A1 | Substituted heteroaryl pyridopyrimidone derivatives | Sanofi-Aventis (FR) | 2008-07-02 | — | — | EP | disclosed |