Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4949145 | 0.98 | TDP1 (0.38) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL21799857 | 0.85 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL632881 | 0.81 | MAPT (0.47) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL9297193 | 0.79 | TAS1R3 (0.41) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL4951647 | 0.78 | ALDH1A1 (0.47) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL21799960 | 0.78 | ALDH1A1 (0.42) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL6671578 | 0.78 | FYN (0.52) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL459453 | 0.78 | FYN (0.52) | TDP1ALDH1A1TSHRL3MBTL1TP53 | |
| SCHEMBL11271222 | 0.78 | ALDH1A1 (0.42) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL6366310 | 0.77 | MAPT (0.51) | ALDH1A1L3MBTL1SMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568684-A1 | para-phenylenediamines carrying an alkoxy group, dye composition, preparation methods and their use | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-20060021158-A1 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1568684-A1 | para-phenylenediamines carrying an alkoxy group, dye composition, preparation methods and their use | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021158-A1 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | KRT18, NOTUM, ALDH7A1 | TDP1 2219/4885ALDH1A1 236/4885TSHR 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.