Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | MMP3 | P08254 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494779 | 1.00 | MMP2 (0.51) | MMP2MMP3TSHRALDH1A1HPGD | |
| SCHEMBL10033245 | 0.84 | MAPT (0.52) | TSHRGAAMAPT | |
| SCHEMBL495932 | 0.82 | MMP2 (0.49) | MMP2MMP3TSHRALDH1A1HPGD | |
| SCHEMBL495930 | 0.82 | MMP2 (0.49) | MMP2MMP3TSHRALDH1A1HPGD | |
| SCHEMBL13806660 | 0.81 | ALDH1A1 (0.55) | MMP2MMP3ALDH1A1HPGDMMP13 | |
| SCHEMBL7661233 | 0.81 | MMP2 (0.56) | MMP2MMP3ALDH1A1HPGDMMP13 | |
| SCHEMBL10033249 | 0.81 | HDAC1 (0.51) | MMP2MMP3ALDH1A1HPGDMMP13 | |
| SCHEMBL13869183 | 0.79 | MMP2 (0.50) | MMP2MMP3ALDH1A1HPGDMMP13 | |
| SCHEMBL9611216 | 0.79 | MMP2 (0.52) | MMP2MMP3ALDH1A1HPGDMMP13 | |
| SCHEMBL181493 | 0.78 | TSHR (0.56) | TSHRALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| EP-1689827-B1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| EP-1689827-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | Rolic AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005054406-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2005-06-16 | — | — | WO | disclosed |