SCHEMBL9611216

SCHEMBL9611216

C=CC(=O)OCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 8/20 0.52
MMP3 P08254 6/20 0.49
MMP1 P03956 1/20 0.49
MMP9 P14780 1/20 0.49
MMP13 P45452 1/20 0.49
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
THRB P10828 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 2/20 0.42
ABCB1 P08183 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
HRH2 P25021 1/20 0.42
HRH1 P35367 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
PTGER4 P35408 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12723890 0.91 MMP2 (0.45) MMP2MMP3MMP1MMP9MMP13
SCHEMBL16449872 0.90 MMP2 (0.44) MMP2MMP3MMP1MMP9MMP13
SCHEMBL16450993 0.90 MAPT (0.45) MMP2MMP3MMP1MMP9MMP13
SCHEMBL12154164 0.90 MMP2 (0.44) MMP2MMP3MMP1MMP9MMP13
SCHEMBL11917942 0.89 THRB (0.53) MMP2MMP3THRBALDH1A1MAPT
SCHEMBL12723896 0.89 THRB (0.42) MMP2MMP3MMP1MMP9MMP13
SCHEMBL12723897 0.89 THRB (0.46) MMP2MMP3MMP1MMP9MMP13
SCHEMBL16425361 0.88 HDAC2 (0.48) MMP2MMP3MMP1MMP9MMP13
SCHEMBL12723894 0.87 RAB9A (0.54) MMP13THRBHRH3
SCHEMBL471107 0.87 THRB (0.61) MMP2MMP3MMP1MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032193-B2 Optical element and method for manufacturing the same AGC Inc. (JP) 2024-07-09 US disclosed
US-20230314854-A1 LIGHT ABSORPTION ANISOTROPIC FILM, VIEWING ANGLE CONTROL SYSTEM, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-10-05 US disclosed
WO-2023189966-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023189967-A1 IDENTIFICATION MEDIUM 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023189788-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023190481-A1 IDENTIFICATION MEDIUM AND PRODUCT 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023190483-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 US disclosed
US-20230176270-A1 OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME AGC Inc. (JP) 2023-06-08 US disclosed
US-20230168543-A1 OPTICAL ELEMENT AGC Inc. (JP) 2023-06-01 US disclosed
US-7449223-B2 containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-11-11 US disclosed
US-20080241431-A1 Polymerizable liquid crystal composition CHISSO CORPORATION 2008-10-02 US disclosed
US-7413782-B2 Polymerizing binaphthalene derivatives CHISSO CORPORATION (JP) 2008-08-19 US disclosed
US-7410677-B2 Organosilicon compound-containing polymerizable liquid-crystal composition CHISSO CORPORATION (JP) 2008-08-12 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-20080152844-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-06-26 US disclosed
US-7378135-B2 Polymerizable liquid crystal composition and optically anisotropic thin film CHISSO CORPORATION (JP) 2008-05-27 US disclosed
US-20080014374-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-01-17 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed