Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 4/20 | 0.58 |
| ▸ | LGALS9 | O00182 | 3/20 | 0.58 |
| ▸ | LGALS1 | P09382 | 3/20 | 0.58 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SELP | P16109 | 6/20 | 0.47 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534423 | 1.00 | LGALS3 (0.58) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL7221498 | 1.00 | LGALS3 (0.58) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL15815859 | 1.00 | LGALS3 (0.58) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL17318202 | 1.00 | LGALS3 (0.58) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL2508264 | 0.98 | LGALS3 (0.56) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL14530940 | 0.98 | LGALS3 (0.56) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL2506760 | 0.98 | LGALS3 (0.56) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL17778306 | 0.93 | LGALS3 (0.52) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL17778430 | 0.93 | LGALS3 (0.52) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 | |
| SCHEMBL7799364 | 0.92 | LGALS3 (0.53) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284741-B1 | 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS | PHARMASSET INC (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1964569-A2 | 3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of viral infections | Pharmasset, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| US-7094770-B2 | 3′-or 2′-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections | PHARMASSET, LTD. (BB) | 2006-08-22 | — | — | US | disclosed |
| EP-1284741-A2 | 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS | Pharmasset, Ltd. (BB) | 2003-02-26 | — | — | EP | disclosed |
| US-20020055483-A1 | 3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatites virus infections | PHARMASSET, INC. | 2002-05-09 | — | — | US | disclosed |
| WO-2001079246-A2 | 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS | PHARMASSET, LTD. (BB) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055483-A1 | 3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatites virus infections | HCCS, HDGF, HMBS | LGALS3 2908/4885LGALS9 3267/4885LGALS1 3333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.