Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.65 |
| ▸ | CKS1B | P61024 | 1/20 | 0.55 |
| ▸ | SKP1 | P63208 | 1/20 | 0.55 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200582 | 0.94 | GPR119 (0.60) | GPR119CKS1BSKP1SKP2NPY5R | |
| SCHEMBL4827630 | 0.94 | GPR119 (0.60) | GPR119CKS1BSKP1SKP2NPY5R | |
| SCHEMBL28856276 | 0.94 | GPR119 (0.60) | GPR119CKS1BSKP1SKP2NPY5R | |
| SCHEMBL21847896 | 0.88 | GPR119 (0.55) | GPR119CKS1BSKP1SKP2KDM4D | |
| SCHEMBL22775604 | 0.87 | GPR119 (0.55) | GPR119CKS1BSKP1SKP2KDM4D | |
| SCHEMBL22774285 | 0.87 | GPR119 (0.55) | GPR119CKS1BSKP1SKP2KDM4D | |
| SCHEMBL29576568 | 0.87 | GPR119 (0.55) | GPR119CKS1BSKP1SKP2KDM4D | |
| SCHEMBL29576692 | 0.87 | GPR119 (0.55) | GPR119CKS1BSKP1SKP2KDM4D | |
| SCHEMBL7487448 | 0.86 | GPR119 (0.52) | GPR119CKS1BSKP1SKP2NPY5R | |
| SCHEMBL1456142 | 0.85 | CKS1B (0.54) | GPR119CKS1BSKP1SKP2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408332-B | Substituted triazolopyridines | 拜耳制药股份公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-2079727-B1 | KINASE INHIBITOR COMPOUNDS | XCOVERY INC (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8524709-B2 | Kinase inhibitor compounds | TYROGENEX, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20120115866-A1 | KINASE INHIBITOR COMPOUNDS | TYROGENEX, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-8039470-B2 | Kinase inhibitor compounds | TYROGENEX, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20100261665-A1 | Kinase inhibitor compounds | XCOVERY, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-7683057-B2 | 5-[5-fluoro-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (1-acetyl-piperidin-4-yl)-amide; inhibition of 5' AMP-activated protein kinase (AMPK) | TYROGENEX, INC. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20090076005-A1 | Kinase inhibitor compounds | XCOVERY, INC. (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076005-A1 | Kinase inhibitor compounds | MAP3K1, MAP3K20, MAP3K2 | GPR119 1851/4885CKS1B 109/4885SKP1 553/4885 |
| US-20120115866-A1 | KINASE INHIBITOR COMPOUNDS | MAP3K1, MAP3K20, MAP3K2 | GPR119 1851/4885CKS1B 109/4885SKP1 553/4885 |
| US-20100261665-A1 | Kinase inhibitor compounds | MAP3K1, MAP3K20, MAP3K2 | GPR119 1851/4885CKS1B 109/4885SKP1 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.