Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25546220 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL10592223 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL18766167 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL15687730 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL21694571 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL17923463 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL21955714 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL21249767 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL21955711 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL9190651 | 0.98 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250235404-A1 | PEG-LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. | 2025-07-24 | — | — | US | disclosed |
| US-20250049948-A1 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME | SAIL BIOMEDICINES, INC. | 2025-02-13 | — | — | US | disclosed |
| EP-4504265-A1 | PEG-LIPIDS AND LIPID NANOPARTICLES | Capstan Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-118829625-A | Novel ionizable lipids and lipid nanoparticles and methods of use thereof | 赛欧生物医药股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| EP-4433450-A1 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME | Sail Biomedicines, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023196445-A1 | PEG-LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023091490-A1 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME | SENDA BIOSCIENCES, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20080297878-A1 | Compositions, methods and systems for making and using electronic paper | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-12-04 | — | — | US | disclosed |
| US-7385064-B1 | Catalysts for use in enantioselective synthesis | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2008-06-10 | — | — | US | disclosed |
| US-7109343-B2 | Metal catalysts and methods for making and using same | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1073645-A2 | PROCESS FOR THE PREPARATION OF TETRALONE IMINES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOUNDS | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| WO-2000064583-A1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-11-02 | — | — | WO | disclosed |
| US-6054614-A | Process for the preparation of tetralone imines for the preparation of active pharmaceutical compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-04-25 | — | — | US | disclosed |
| WO-1999055686-A2 | PROCESS FOR THE PREPARATION OF TETRALONE IMINES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-11-04 | — | — | WO | disclosed |
| US-4556676-A | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine | PFIZER INC. (US) | 1985-12-03 | — | — | US | disclosed |
| US-4536518-A | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine | PFIZER INC. (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0030081-B1 | ANTIDEPRESSANT DERIVATIVES OF CIS-4-PHENYL-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0028901-B1 | ANTIDEPRESSANT DERIVATIVES OF TRANS-4-PHENYL-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0030081-A1 | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine and pharmaceutical compositions thereof | PFIZER INC. (US) | 1981-06-10 | — | — | EP | disclosed |
| EP-0028901-A1 | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine and pharmaceutical compositions thereof | PFIZER INC. (US) | 1981-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235404-A1 | PEG-LIPIDS AND LIPID NANOPARTICLES | LNPEP, HDLBP, PLTP | FFAR4 1215/4885FFAR1 1491/4885AKR1B1 4451/4885 |
| US-20250049948-A1 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME | NPC1L1, ABCB4, LIPA | FFAR4 1480/4885FFAR1 1722/4885AKR1B1 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.