Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10011415 | 0.82 | TSHR (0.40) | TSHRSLC1A2MEN1KMT2ACHRNB2 | |
| SCHEMBL14353237 | 0.82 | KMT2A (0.47) | TSHRSLC1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19105368 | 0.81 | TSHR (0.38) | TSHRSLC1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10011145 | 0.81 | ADRA2A (0.32) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10012313 | 0.80 | TSHR (0.39) | TSHRSLC1A2MEN1KMT2ACHRNB2 | |
| SCHEMBL7105090 | 0.79 | SMN1; SMN2 (0.46) | TSHRKMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL25260976 | 0.79 | KMT2A (0.36) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL12792630 | 0.79 | KMT2A (0.36) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL10012604 | 0.79 | TSHR (0.38) | TSHRSLC1A2MEN1KMT2ACHRNB2 | |
| SCHEMBL6830271 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399883-B2 | Process for making adipic acid | INVISTA NORTH AMERICA S.A.R.L. (US) | 2008-07-15 | — | — | US | disclosed |
| US-20060258876-A1 | Process for making 5-cyanovaleric acid, adipic acid or dimethyl adipate | INVISTA NORTH AMERICA S.AR.L. (US) | 2006-11-16 | — | — | US | disclosed |
| US-7078555-B2 | Process for making 5-cyanovaleric acid, adipic acid or dimethyl adipate | INVISTA NORTH AMERICA S.A.R.L. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040162440-A1 | PROCESS FOR MAKING 5-CYANOVALERIC ACID, ADIPIC ACID OR DIMETHYL ADIPATE | INVISTA NORTH AMERICA S.A.R.L. | 2004-08-19 | — | — | US | disclosed |
| EP-1341751-A1 | tROCESS FOR MAKING 5-CYANOVALERIC ACID, ADIPIC ACID OR DIMETHYL ADIDPATE | INVISTA Technologies S.à.r.l. (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20030105348-A1 | Process for making 5-cyanovaleric acid, adipic acid or dimethyl adipate | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-06-05 | — | — | US | disclosed |
| WO-2002048094-A1 | tROCESS FOR MAKING 5-CYANOVALERIC ACID, ADIPIC ACID OR DIMETHYL ADIDPATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-4508660-A | Carbonylation of olefinically unsaturated nitriles and acids using a sulfone solvent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4060543-A | Manufacture of 5-cyanovaleric acid and its esters | BASF AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105348-A1 | Process for making 5-cyanovaleric acid, adipic acid or dimethyl adipate | ALKBH3, ALKBH1, ADIPOR1 | TSHR 2877/4885SLC1A2 563/4885MEN1 971/4885 |
| US-20040162440-A1 | PROCESS FOR MAKING 5-CYANOVALERIC ACID, ADIPIC ACID OR DIMETHYL ADIPATE | ALKBH3, ALKBH1, ADIPOR1 | TSHR 2877/4885SLC1A2 563/4885MEN1 971/4885 |
| US-20060258876-A1 | Process for making 5-cyanovaleric acid, adipic acid or dimethyl adipate | ADIPOR1, ALKBH3, ADIPOR2 | TSHR 659/4885SLC1A2 1534/4885MEN1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.