SCHEMBL49552

SCHEMBL49552

O=c1c2ccccc2oc2cccc(Cl)c12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 10/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 1/20 0.63
GLA P06280 1/20 0.63
CYP3A4 P08684 1/20 0.63
MAPT P10636 1/20 0.63
HPGD P15428 1/20 0.63
PGAM1 P18669 1/20 0.63
CASP1 P29466 1/20 0.63
CASP7 P55210 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
HSD17B10 Q99714 1/20 0.63
TTR P02766 2/20 0.60
MGAM O43451 1/20 0.51
GAA P10253 1/20 0.51
SI P14410 1/20 0.51
MGAM2 Q2M2H8 1/20 0.51
NMUR2 Q9GZQ4 1/20 0.51
KDM5A P29375 1/20 0.50
ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30618440 1.00 MAOA (0.63) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL20346644 0.87 MAOA (0.53) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL20346625 0.86 MAOA (0.56) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30490062 0.84 AHR (0.55) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL472793 0.84 AHR (0.55) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL11572006 0.81 MAOA (0.59) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL31193506 0.81 MGAM (0.74) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL9835098 0.81 MGAM (0.74) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL20317219 0.81 TTR (0.57) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL20346635 0.81 TTR (0.50) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327088-A Novel chloroxanthone compound and preparation method and application thereof 三峡大学 2024-01-02 CN claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
CN-104177324-B Xanthone compound and antidepressant application thereof NANJING TECH UNIVERSITY (CN) 2016-05-11 CN claimed
CN-104177324-A Xanthone compound and antidepressant application thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-12-03 CN claimed
US-20110123721-A1 ENZYMATIC SYNTHESIS OF POLYOL ACRYLATES BASF AKTIENGESELLSCHAFT (DE) 2011-05-26 US claimed
EP-1051665-B1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME ALBEMARLE CORP (US) 2006-07-12 EP claimed
US-6555593-B1 Maleimides with a benzophenone compound/hydrogen atom donor sensitizer system activated by irradiation ALBEMARLE CORPORATION 2003-04-29 US claimed
CN-1295680-A Photopolymerization compositions including maleimides and processes for using the same FIRST CHEMICAL CORP (US) 2001-05-16 CN claimed
EP-1051665-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME First Chemical Corporation (US) 2000-11-15 EP claimed
WO-1999039247-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME FIRST CHEMICAL CORPORATION (US) 1999-08-05 WO claimed
WO-1995011927-A1 POLYESTER-MODIFIED POLYDIENE/ACRYLOURETHANE OLIGOMERS LORD CORPORATION (US) 1995-05-04 WO claimed
US-12559631-B2 Thermally curable two-component coating compounds BASF SE (DE) 2026-02-24 US disclosed
US-20250368830-A1 METHOD FOR TRANSFERRING AN EMBOSSED STRUCTURE TO THE SURFACE OF A COATING, AND COMPOSITE EMPLOYABLE AS EMBOSSING MOLD BASF COATINGS GMBH (DE) 2025-12-04 US disclosed
US-4399209-A Transfer imaging system THE MEAD CORPORATION (US) 1983-08-16 US disclosed
US-4292107-A ULTRAVIOLET-RADIATION CURING OF A COATING OF A DISPERSION OF PHORPHOR IN A BINDER OF UNSATURATED POLYMER AND MONOMER AND SENSITIZER KASEI OPTONIX, LTD. (JP) 1981-09-29 US disclosed
US-4120721-A ACRYLIC OR METHACRYLIC TERMINATED, URETHANE CONTAINING POLYENE; WATER INSOLUBLE VINYL MONOMER DILUENT; POLYTHIOL; PHOTOINITIATOR W. R. GRACE & CO. (US) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559631-B2 Thermally curable two-component coating compounds ESD, MGMT, MTHFD2 MAOA 1983/4885KDM4E 2127/4885ALDH1A1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.