Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935885 | 0.86 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL9156343 | 0.86 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL4887935 | 0.85 | CYP1A2 (0.61) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL11157053 | 0.84 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL17258977 | 0.83 | CYP1A2 (0.59) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL5085511 | 0.79 | HTT (0.49) | CYP2D6CYP2C9ALDH1A1HPGDHTT | |
| SCHEMBL25217366 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL27682450 | 0.79 | ALDH1A1 (0.53) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL6920617 | 0.78 | PLAU (0.53) | HTT | |
| SCHEMBL3559924 | 0.77 | RIPK1 (0.58) | TSHRALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081789-A1 | BETA PEPTOIDS WITH ANTIMICROBIAL ACTIVITY | SHUEY STEVEN W | 2008-04-03 | — | — | US | disclosed |
| US-7307061-B2 | β-peptoids with antimicrobial activity | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-12-11 | — | — | US | disclosed |
| US-20060160735-A1 | Beta-peptoids with antimicrobial activity | DUPONT US HOLDING, LLC | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081789-A1 | BETA PEPTOIDS WITH ANTIMICROBIAL ACTIVITY | PEPD, VIP, CLPP | CYP1A2 4342/4885CYP2D6 4281/4885CYP2C9 3944/4885 |
| US-20060160735-A1 | Beta-peptoids with antimicrobial activity | VIP, PEPD, PREP | CYP1A2 4172/4885CYP2D6 4154/4885CYP2C9 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.