Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174122 | 0.93 | LMNA (0.38) | PTPN1ALDH1A1LMNACYP2D6SPHK1 | |
| SCHEMBL3630693 | 0.84 | PTPN1 (0.39) | PTPN1ALDH1A1LMNACYP2D6SPHK1 | |
| SCHEMBL18136267 | 0.84 | LMNA (0.37) | LMNATSHR | |
| SCHEMBL15044040 | 0.84 | LMNA (0.37) | LMNATSHR | |
| SCHEMBL15895084 | 0.84 | LMNA (0.37) | LMNATSHR | |
| SCHEMBL1661707 | 0.81 | THRB (0.36) | PTPN1LMNATRPV1TRPA1 | |
| SCHEMBL31461000 | 0.80 | SPHK1 (0.52) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL15484312 | 0.79 | LMNA (0.53) | PTPN1LMNACYP2D6SPHK1GMNN | |
| SCHEMBL14556007 | 0.79 | LMNA (0.38) | ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL20474203 | 0.78 | SMN1; SMN2 (0.43) | PTPN1ALDH1A1LMNACYP2D6SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960450-A2 | POLYURETHANES, POLYURETHANE(UREAS) SULFUR-CONTAINING POLYURETHANES AND SULFUR-CONTAINING POLYURETHANE(UREAS) AND METHODS OF PREPARATION | PPG Industries Ohio, Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007078549-A2 | POLYURETHANES, POLYURETHANE(UREAS) SULFUR-CONTAINING POLYURETHANES AND SULFUR-CONTAINING POLYURETHANE(UREAS) AND METHODS OF PREPARATION | PPG INDUSTRIES OHIO, INC. (US) | 2007-07-12 | — | — | WO | disclosed |