Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15895084 | 1.00 | LMNA (0.37) | LMNATHRBTSHRL3MBTL1TDP1 | |
| SCHEMBL18136267 | 1.00 | LMNA (0.37) | LMNATHRBTSHRL3MBTL1TDP1 | |
| SCHEMBL14556007 | 0.94 | LMNA (0.38) | LMNATHRBTSHRL3MBTL1TDP1 | |
| SCHEMBL15484277 | 0.85 | THRB (0.44) | LMNATHRBL3MBTL1TDP1 | |
| SCHEMBL4956291 | 0.84 | PTPN1 (0.37) | LMNATSHR | |
| SCHEMBL6436093 | 0.83 | LMNA (0.48) | LMNATHRBTSHRL3MBTL1TDP1 | |
| SCHEMBL8855937 | 0.82 | — | — | |
| SCHEMBL8855929 | 0.82 | — | — | |
| SCHEMBL395052 | 0.82 | — | — | |
| SCHEMBL3174122 | 0.82 | LMNA (0.38) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024023138-A2 | CA-IX TARGETING FLUORESCENT PROBES | BRACCO IMAGING SPA (IT) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024023144-A1 | CA-IX TARGETING FLUORESCENT PROBES | BRACCO IMAGING SPA (IT) | 2024-02-01 | — | — | WO | disclosed |
| WO-2021259899-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING SPA (IT) | 2021-12-30 | — | — | WO | disclosed |
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | SHIONOGI & CO (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-2700636-B1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | ASAHI CHEMICAL IND (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9550763-B2 | Heterocyclic ring and carbocyclic derivative | SHIONOGI & CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-9359324-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | SHIONOGI & CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-16 | — | — | US | disclosed |
| US-9051293-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-04-17 | — | — | US | disclosed |
| EP-2700636-A1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | Asahi Kasei Chemicals Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| WO-2013089212-A1 | SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | P2RX3, P2RX7, P2RX2 | LMNA 3635/4885THRB 747/4885TSHR 737/4885 |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | P2RX3, P2RX7, P2RX2 | LMNA 3635/4885THRB 747/4885TSHR 737/4885 |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | LMNA 3658/4885THRB 962/4885TSHR 1233/4885 |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | LMNA 3658/4885THRB 962/4885TSHR 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.