SCHEMBL4956502

SCHEMBL4956502

COC(=O)N(OC(=O)c1ccccc1)C(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
LMNA P02545 2/20 0.48
F2 P00734 1/20 0.48
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 4/20 0.46
SLC6A3 Q01959 2/20 0.46
PKM P14618 2/20 0.46
MAPT P10636 6/20 0.44
RAB9A P51151 4/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
SLC6A2 P23975 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10938756 0.80 LMNA (0.51) TSHRLMNAALDH1A1KMT2ASLC6A3
SCHEMBL8778267 0.80 TSHR (0.54) TSHRLMNAF2ALDH1A1KMT2A
SCHEMBL8778288 0.78 LMNA (0.54) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL29831725 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL29105567 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL29039896 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL28537345 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL28945661 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL1332323 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A
Methyl Benzoate SCHEMBL7200 0.77 TSHR (1.00) TSHRLMNAF2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1874722-B1 HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF AMOREPACIFIC CORP (KR) 2015-04-08 EP disclosed
EP-1874722-A1 HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF Amorepacific Corporation (KR) 2008-01-09 EP disclosed
WO-2006118380-A1 HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF AMOREPACIFIC CORPORATION (KR) 2006-11-09 WO disclosed