SCHEMBL8778267

SCHEMBL8778267

CC(=O)N(OC(=O)c1ccccc1)C(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
LMNA P02545 2/20 0.52
F2 P00734 1/20 0.52
KMT2A Q03164 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 1/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
PKM P14618 2/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 3/20 0.44
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14354319 0.82 TDP1 (0.55) LMNAKMT2ATDP1ALDH1A1CES2
SCHEMBL13604012 0.82 TSHR (0.52) TSHRLMNAF2KMT2ATDP1
SCHEMBL8778288 0.81 LMNA (0.54) TSHRLMNAF2KMT2ATDP1
SCHEMBL4956502 0.80 TSHR (0.61) TSHRLMNAF2KMT2ATDP1
SCHEMBL3986710 0.80 TSHR (0.50) TSHRLMNAF2KMT2ATDP1
SCHEMBL23685579 0.79 TSHR (0.53) TSHRLMNAF2KMT2ATDP1
SCHEMBL28603710 0.79 TSHR (0.48) TSHRLMNAF2KMT2ATDP1
SCHEMBL229327 0.78 TSHR (0.58) TSHRLMNAF2KMT2ATDP1
SCHEMBL23685584 0.77 TSHR (0.47) TSHRLMNAF2KMT2ATDP1
SCHEMBL27469371 0.77 TSHR (0.56) TSHRLMNAF2KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102856586-B Nonaqueous secondary battery and flame retardant for use in the same SHARP KK 2015-01-14 CN claimed
US-9147907-B2 Nonaqueous electrolyte and lithium ion rechargeable battery SHARP KABUSHIKI KAISHA (JP) 2015-09-29 US disclosed
US-9147907-B2 Nonaqueous electrolyte and lithium ion rechargeable battery SHARP KABUSHIKI KAISHA (JP) 2015-09-29 US disclosed
US-9147907-B2 Nonaqueous electrolyte and lithium ion rechargeable battery SHARP KABUSHIKI KAISHA (JP) 2015-09-29 US disclosed
US-9130245-B2 Nonaqueous secondary battery and flame retardant for use in the same SHARP KABUSHIKI KAISHA (JP) 2015-09-08 US disclosed
US-9130245-B2 Nonaqueous secondary battery and flame retardant for use in the same SHARP KABUSHIKI KAISHA (JP) 2015-09-08 US disclosed
US-9130245-B2 Nonaqueous secondary battery and flame retardant for use in the same SHARP KABUSHIKI KAISHA (JP) 2015-09-08 US disclosed
CN-102856586-B Nonaqueous secondary battery and flame retardant for use in the same SHARP KK 2015-01-14 CN disclosed
CN-103347523-A Administration of lorcaserin to a subject having renal injury ARENA PHARM INC 2013-10-09 CN disclosed
US-20130004839-A1 NONAQUEOUS SECONDARY BATTERY AND FLAME RETARDANT FOR USE IN THE SAME SHARP KABUSHIKI KAISHA (JP) 2013-01-03 US disclosed
US-20130004839-A1 NONAQUEOUS SECONDARY BATTERY AND FLAME RETARDANT FOR USE IN THE SAME SHARP KABUSHIKI KAISHA (JP) 2013-01-03 US disclosed
CN-102856586-A Nonaqueous secondary battery and flame retardant for use in the same SHARP KK 2013-01-02 CN disclosed
US-20120328937-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM ION RECHARGEABLE BATTERY SHARP KABUSHIKI KAISHA (JP) 2012-12-27 US disclosed
US-20120328937-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM ION RECHARGEABLE BATTERY SHARP KABUSHIKI KAISHA (JP) 2012-12-27 US disclosed
US-20120328937-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM ION RECHARGEABLE BATTERY SHARP KABUSHIKI KAISHA (JP) 2012-12-27 US disclosed
EP-0576622-B1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK CO (US) 1997-11-05 EP disclosed
EP-0576622-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
WO-1992017821-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1992-10-15 WO disclosed
US-5141839-A LITHOGRAPHIC PRINTING PLATES HAVING A RADIATION-SENSITIVE LAYER COMPRISING A PHOTOCROSSLINKABLE POLYMER, A LEUCO DYE, A PHOTOOXIDANT AND A HETEROAROMATIC AMINE N-OXIDE EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
US-5141842-A Negative working lithography printing plates EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed