Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115556 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CNR2POLBATM | |
| SCHEMBL9267796 | 0.78 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2CNR2POLBATM | |
| SCHEMBL2914479 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CNR2POLBATM | |
| SCHEMBL121153 | 0.72 | LMNA (0.53) | ALDH1A1SMN1; SMN2POLBATMMEN1 | |
| SCHEMBL756264 | 0.71 | ALDH1A1 (0.54) | ALDH1A1GAAPKMLMNATSHR | |
| Water SCHEMBL3002925 | 0.71 | LMNA (0.51) | ALDH1A1SMN1; SMN2POLBATMMEN1 | |
| Ammonia Solution, Strong SCHEMBL1924833 | 0.71 | LMNA (0.51) | ALDH1A1SMN1; SMN2POLBATMMEN1 | |
| Hydrochloric Acid SCHEMBL5858440 | 0.71 | LMNA (0.51) | ALDH1A1SMN1; SMN2POLBATMMEN1 | |
| SCHEMBL907691 | 0.71 | GAA (0.50) | ALDH1A1SMN1; SMN2POLBATMMEN1 | |
| SCHEMBL9514844 | 0.70 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990348-A2 | Metathesis catalysts containing sulphur | Evonik Degussa GmbH (DE) | 2008-11-12 | — | — | EP | disclosed |