SCHEMBL4956830

SCHEMBL4956830

CCCCCc1nc(F)c[nH]1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
GPR84 Q9NQS5 5/20 0.40
PI4KA P42356 1/20 0.37
PI4K2B Q8TCG2 1/20 0.37
PI4K2A Q9BTU6 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5897906 0.78 ALDH1A1 (0.43) ALDH1A1PKMHPGDGPR84KCNH2
SCHEMBL1063754 0.78 KCNH2 (0.47) ALDH1A1PKMHPGDGPR84PI4KA
SCHEMBL730079 0.77 KCNH2 (0.50) ALDH1A1PKMHPGDGPR84KCNH2
SCHEMBL83498 0.77 ALDH1A1 (0.46) ALDH1A1PKMHPGDGPR84KCNH2
SCHEMBL4374043 0.77 PI4KA (0.44) ALDH1A1PKMHPGDGPR84PI4KA
SCHEMBL24880067 0.77 ALDH1A1 (0.46) ALDH1A1PKMHPGDGPR84KCNH2
SCHEMBL9817100 0.77 KCNH2 (0.50) ALDH1A1PKMHPGDGPR84KCNH2
SCHEMBL1230952 0.77 ALDH1A1 (0.42) ALDH1A1PKMHPGDGPR84PI4KA
SCHEMBL6060906 0.77 ALDH1A1 (0.42) ALDH1A1PKMHPGDGPR84PI4KA
SCHEMBL4445935 0.77 KCNH2 (0.50) ALDH1A1PKMHPGDGPR84KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118263523-A Use of acyl imidazoles 陕西奥林波斯电力能源有限责任公司 2024-06-28 CN claimed
CN-118263523-A Use of acyl imidazoles 陕西奥林波斯电力能源有限责任公司 2024-06-28 CN disclosed
US-7435713-B2 Compositions and methods for removal of incidental soils from fabric articles via soil modification THE PROCTER & GAMBLE COMPANY (US) 2008-10-14 US disclosed
EP-1451403-B1 COMPOSITIONS AND METHODS FOR REMOVAL OF INCIDENTAL SOILS FROM FABRIC ARTICLES VIA SOIL MODIFICATION PROCTER & GAMBLE (US) 2006-10-04 EP disclosed
US-20050137108-A1 Compositions and methods for removal of incidental soils from fabric articles via soil modification THE PROCTER & GAMBLE COMPANY 2005-06-23 US disclosed
US-6890892-B2 Compositions and methods for removal of incidental soils from fabric articles via soil modification PROCTER & GAMBLE COMPANY (US) 2005-05-10 US disclosed
EP-1451403-A1 COMPOSITIONS AND METHODS FOR REMOVAL OF INCIDENTAL SOILS FROM FABRIC ARTICLES VIA SOIL MODIFICATION THE PROCTER & GAMBLE COMPANY (US) 2004-09-01 EP disclosed
US-20030119711-A1 Compositions and methods for removal of incidental soils from fabric articles via soil modification PROCTOR & GAMBLE COMPANY, THE 2003-06-26 US disclosed
WO-2003050344-A1 COMPOSITIONS AND METHODS FOR REMOVAL OF INCIDENTAL SOILS FROM FABRIC ARTICLES VIA SOIL MODIFICATION THE PROCTER & GAMBLE COMPANY (US) 2003-06-19 WO disclosed