Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 3/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24812797 | 0.92 | MAPT (0.53) | MAPTADORA2BGDAACHEENPP1 | |
| SCHEMBL29811206 | 0.74 | XDH (0.50) | MAPTADORA2BGDAACHEXDH | |
| SCHEMBL10997 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEXDH | |
| SCHEMBL30728071 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEXDH | |
| SCHEMBL4372319 | 0.73 | MAPT (0.44) | MAPTADORA2BGDAACHEENPP1 | |
| SCHEMBL11642909 | 0.73 | MAPT (0.44) | MAPTADORA2BGDAACHEENPP1 | |
| SCHEMBL29737730 | 0.72 | KDM4C (0.45) | MAPTADORA2BGDAACHEXDH | |
| SCHEMBL9515047 | 0.71 | MAPT (0.50) | MAPTADORA2BGDAACHEXDH | |
| SCHEMBL517356 | 0.70 | MAPT (0.46) | MAPTADORA2BGDAACHEENPP1 | |
| SCHEMBL932949 | 0.69 | MAPT (0.53) | MAPTADORA2BGDAACHEXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393662-B2 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses | CENTOCOR, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20060051844-A1 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses | CNA DEVELOPMENT GMBH (CH) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051844-A1 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses | EPOR, GHITM, HBB | MAPT 3023/4885ADORA2B 4020/4885GDA 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.