Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958146 | 0.95 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL29361802 | 0.81 | SIRT2 (0.45) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL44480 | 0.81 | SIRT2 (0.45) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL16765694 | 0.81 | SIRT2 (0.45) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL6668083 | 0.81 | HDAC3 (0.41) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL6647077 | 0.80 | F12 (0.37) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL27529584 | 0.80 | SIRT2 (0.44) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL1674867 | 0.79 | NPSR1 (0.39) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL4958670 | 0.77 | FAAH (0.34) | MAPT | |
| SCHEMBL3580017 | 0.77 | NPSR1 (0.39) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453860-A2 | NOVEL GLUCOSE-DEPENDANT INSULINS | NOVO NORDISK A/S (DK) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048195-A2 | GLUCOSE DEPENDANT RELEASE OF INSULIN FROM GLUCOSE SENSING INSULIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |