Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765348 | 0.80 | HTR2A (0.37) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL2290547 | 0.74 | HTR2A (0.39) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL8036851 | 0.72 | HTR2A (0.50) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL11884483 | 0.71 | HTR2A (0.37) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL6420010 | 0.67 | HTR2A (0.50) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL10080430 | 0.67 | HTR2A (0.56) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL1276091 | 0.67 | HTR2A (0.50) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL31099344 | 0.67 | HTR2A (0.50) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL5679950 | 0.67 | HTR2A (0.50) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL11875463 | 0.67 | BRD4 (0.53) | HTR2ACYP2D6KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118664-A1 | Process for the Preparation of Fluorinated Diazoalkanes | RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2018-05-03 | — | — | US | disclosed |
| US-7678394-B2 | Analytical methods for identifying ginseng varieties | SHEN BAIHUA | 2010-03-16 | — | — | US | disclosed |
| US-20080175929-A1 | ANALYTICAL METHODS FOR IDENTIFYING GINSENG VARIETIES | SHEN BAIHUA | 2008-07-24 | — | — | US | disclosed |
| EP-1940516-A2 | BENZOPYRAN AND PYRANOPYRIDINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | Janssen Pharmaceutica, N.V. (BE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1937669-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007027959-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027780-A2 | BENZOPYRAN AND PYRANOPYRIDINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118664-A1 | Process for the Preparation of Fluorinated Diazoalkanes | FLNA, PFAS, FLNB | HTR2A 2428/4885CYP2D6 866/4885KDM4E 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.