Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.95 |
| ▸ | CA9 | Q16790 | 11/20 | 0.95 |
| ▸ | CA1 | P00915 | 7/20 | 0.95 |
| ▸ | CA3 | P07451 | 7/20 | 0.95 |
| ▸ | CA4 | P22748 | 7/20 | 0.95 |
| ▸ | CA7 | P43166 | 7/20 | 0.95 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.95 |
| ▸ | CA5A | P35218 | 6/20 | 0.95 |
| ▸ | CA6 | P23280 | 6/20 | 0.95 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.95 |
| ▸ | CA2 | P00918 | 5/20 | 0.95 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.95 |
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.95 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL29168819 | 1.00 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL6252 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL28886137 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL29385611 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL621751 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL3441294 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL1038138 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL8144767 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL382038 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL531571 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629197-B2 | Chemically patterned hydrogels, manufacture and use thereof | SHOICHET MOLLY (CA) | 2014-01-14 | — | — | US | disclosed |
| US-20080286360-A1 | Chemically patterned hydrogels, manufacture and use thereof | SHOICHET MOLLY | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286360-A1 | Chemically patterned hydrogels, manufacture and use thereof | CD44, CRYAA, VCL | CA12 1347/4885CA9 1306/4885CA1 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.