Pivalate

Pivalate

SCHEMBL4958539

CC(C)(C)C(=O)O.CCCCOOCCCC

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
TSHR P16473 7/20 0.39
TDP1 Q9NUW8 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HPGD P15428 1/20 0.39
AKR1B1 P15121 1/20 0.37
MAPK1 P28482 2/20 0.37
CA2 P00918 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
PPARG P37231 4/20 0.36
PPARD Q03181 4/20 0.36
PPARA Q07869 4/20 0.36
GPR84 Q9NQS5 3/20 0.36
HDAC11 Q96DB2 3/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
TLR2 O60603 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pivalate SCHEMBL27493603 0.93 NAAA (0.43) ALDH1A1HCAR2TSHRTDP1AKR1B1
Pivalate SCHEMBL27427306 0.91 NAAA (0.47) ALDH1A1HCAR2TSHRTDP1PPARG
Pivalate SCHEMBL27959698 0.86 ALDH1A1 (0.47) ALDH1A1ATMHCAR2TSHRHPGD
Bicarbonate SCHEMBL1538407 0.85 ALDH1A1 (0.52) ALDH1A1ATMHCAR2TSHRTDP1
SCHEMBL475085 0.83 ALDH1A1 (0.39) ALDH1A1ATMHCAR2TSHRTDP1
Acetic Acid SCHEMBL2136672 0.82 ALDH1A1 (0.56) ALDH1A1ATMHCAR2TSHRTDP1
Pivalate SCHEMBL10837336 0.82 AKR1B1 (0.52) ALDH1A1TSHRTDP1AKR1B1PPARG
SCHEMBL474943 0.80 ALDH1A1 (0.40) ALDH1A1ATMHCAR2TSHRHPGD
Pivalate SCHEMBL30969421 0.80 NAAA (0.37) ALDH1A1HCAR2TSHRAKR1B1TP53
Octane SCHEMBL29057202 0.79 GPR84 (0.55) ALDH1A1TSHRTDP1AKR1B1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108126541-A Kynoar Thermo-sensitive film and preparation method thereof 济南大学 2018-06-08 CN claimed
CN-102666609-A High pressure LDPE for medical applications BASELL POLYOLEFINE GMBH 2012-09-12 CN disclosed
EP-1943279-A1 METHOD OF PREPARING VINYLCHLORIDE-BASED RESIN CAPABLE OF PRODUCING PLASTISOL WITH LOW VISCOSITY, VINYLCHLORIDE-BASED RESIN PREPARED USING THE METHOD, METHOD OF PREPARING VINYLCHLORIDE-BASED PLASTISOL, AND VINYLCHLORIDE-BASED PLASTISOL PREPARED USING THE METHOD LG Chem. Ltd. (KR) 2008-07-16 EP disclosed
WO-2007052911-A1 METHOD OF PREPARING VINYLCHLORIDE-BASED RESIN CAPABLE OF PRODUCING PLASTISOL WITH LOW VISCOSITY, VINYLCHLORIDE-BASED RESIN PREPARED USING THE METHOD, METHOD OF PREPARING VINYLCHLORIDE-BASED PLASTISOL, AND VINYLCHLORIDE-BASED PLASTISOL PREPARED USING THE METHOD LG CHEM, LTD. (KR) 2007-05-10 WO disclosed