Succinic Acid Diethyl Ester

Succinic Acid Diethyl Ester

SCHEMBL4959014

CCOC(=O)CCC(=O)OCC.O=C1CCCCC1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
ALDH1A1 P00352 5/20 0.44
GAA P10253 2/20 0.44
TRIM24 O15164 2/20 0.44
TRIM33 Q9UPN9 2/20 0.44
CYP1A2 P05177 1/20 0.44
TSHR P16473 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
CYP2D6 P10635 1/20 0.43
LMNA P02545 2/20 0.42
POLB P06746 1/20 0.42
BRD4 O60885 1/20 0.41
NOTUM Q6P988 1/20 0.41
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexanone SCHEMBL15347719 0.88 BRD4 (0.40) PARP1CYP4F2CYP4A11ALDH1A1GAA
Succinic Acid Diethyl Ester SCHEMBL27646294 0.85 GAA (0.57) CYP4F2CYP4A11ALDH1A1GAACYP1A2
Cyclohexanone SCHEMBL28118787 0.83 KMT2A (0.44) ALDH1A1GAATRIM24TRIM33TSHR
Cyclohexanone SCHEMBL2854654 0.82 ALDH1A1 (0.46) ALDH1A1GAATRIM24TRIM33MGAM
Cyclohexanone SCHEMBL2259986 0.82 ALDH1A1 (0.58) ALDH1A1GAATRIM24TRIM33TSHR
Cycloheptanone SCHEMBL10412695 0.82 ALDH1A1 (0.58) ALDH1A1GAATRIM24TRIM33TSHR
Cyclohexanone SCHEMBL28249010 0.80 ALOX15 (0.60) ALDH1A1GAATRIM24TRIM33CYP2D6
Ethyl Acetate SCHEMBL7986575 0.79 ALDH1A1 (0.61) ALDH1A1GAATRIM24TRIM33TSHR
Cyclopentanone SCHEMBL3267093 0.79 TRIM24 (0.43) ALDH1A1GAATRIM24TRIM33MGAM
SCHEMBL28105445 0.78 CYP4F2 (0.43) PARP1CYP4F2CYP4A11ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1748866-A4 MOLECULAR MEMORY AND PROCESSING SYSTEMS AND METHODS THEREFOR ZETTACORE INC (US) 2008-09-10 EP disclosed
EP-1748866-A2 MOLECULAR MEMORY AND PROCESSING SYSTEMS AND METHODS THEREFOR Zettacore, Inc. (US) 2007-02-07 EP disclosed
WO-2006031260-A2 MOLECULAR MEMORY AND PROCESSING SYSTEMS AND METHODS THEREFOR ZETTACORE, INC. (US) 2006-03-23 WO disclosed