Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960079 | 0.89 | OPRL1 (0.35) | POLBOPRL1 | |
| SCHEMBL4313590 | 0.83 | POLB (0.37) | POLBOPRL1 | |
| SCHEMBL4962541 | 0.79 | HRH3 (0.35) | POLB | |
| SCHEMBL4315951 | 0.79 | POLB (0.37) | POLBCNR1 | |
| SCHEMBL4308048 | 0.78 | POLB (0.35) | POLBCNR1 | |
| SCHEMBL4311381 | 0.77 | POLB (0.39) | POLBCNR1 | |
| SCHEMBL4308697 | 0.76 | POLB (0.36) | POLBCNR1 | |
| SCHEMBL4318842 | 0.76 | MGLL (0.42) | POLB | |
| SCHEMBL4307945 | 0.75 | EPHX2 (0.42) | POLB | |
| SCHEMBL4316140 | 0.75 | LMNA (0.42) | POLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-B1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-10-09 | — | — | EP | disclosed |
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |