Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962457 | 0.92 | F2 (0.35) | HRH3POLBKCNH2FKBP1A | |
| SCHEMBL4962104 | 0.88 | HCRTR1 (0.35) | HRH3KCNH2 | |
| SCHEMBL4306705 | 0.83 | SPR (0.44) | POLB | |
| SCHEMBL4959440 | 0.79 | POLB (0.36) | POLB | |
| SCHEMBL13667456 | 0.79 | FAAH (0.47) | POLB | |
| SCHEMBL4306732 | 0.79 | FAAH (0.47) | POLB | |
| SCHEMBL13667455 | 0.79 | FAAH (0.47) | POLB | |
| SCHEMBL4313230 | 0.78 | KMT2A (0.43) | POLB | |
| SCHEMBL4312834 | 0.78 | CYP3A4 (0.39) | — | |
| SCHEMBL4960079 | 0.77 | OPRL1 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |