Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961290 | 0.86 | SLC6A2 (0.44) | SPRFAAHGRIN2BCHRM4ENPP2 | |
| SCHEMBL4959675 | 0.82 | FAAH (0.39) | SPRFAAHMEN1KMT2APRMT5 | |
| SCHEMBL4959847 | 0.81 | CCR3 (0.39) | SPRFAAHPRMT5WDR77 | |
| SCHEMBL4310234 | 0.81 | SPR (0.47) | SPRFAAHMEN1KMT2ACNR1 | |
| SCHEMBL4957412 | 0.80 | FAAH (0.47) | SPRFAAHGRIN2BMEN1KMT2A | |
| SCHEMBL4958259 | 0.78 | FAAH (0.41) | SPRFAAHGRIN2BMEN1KMT2A | |
| SCHEMBL4958229 | 0.77 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL4958443 | 0.76 | POLB (0.39) | FAAHGRIN2BCHRM4PRMT5WDR77 | |
| SCHEMBL4312902 | 0.76 | SPR (0.45) | SPRFAAHGRIN2BMEN1KMT2A | |
| SCHEMBL4958786 | 0.76 | POLB (0.37) | KMT2ACNR1CNR2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |