Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958443 | 0.90 | POLB (0.39) | POLBPRMT5WDR77ALDH1A1NPC1 | |
| SCHEMBL4959588 | 0.85 | PSEN1 (0.38) | — | |
| SCHEMBL4308697 | 0.82 | POLB (0.36) | POLBALDH1A1GRM5GRM7GRM3 | |
| SCHEMBL4959675 | 0.81 | FAAH (0.39) | PRMT5WDR77KMT2A | |
| SCHEMBL4958229 | 0.81 | PRMT5 (0.41) | PRMT5WDR77NPC1 | |
| SCHEMBL4959925 | 0.79 | ENPP2 (0.43) | — | |
| SCHEMBL4957412 | 0.79 | FAAH (0.47) | PRMT5WDR77ALDH1A1KMT2A | |
| SCHEMBL4308048 | 0.78 | POLB (0.35) | POLBALDH1A1GRM5GRM7GRM3 | |
| SCHEMBL4958190 | 0.78 | MGLL (0.42) | ALDH1A1NPC1KMT2A | |
| SCHEMBL4958259 | 0.78 | FAAH (0.41) | PRMT5WDR77ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |