Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959835 | 0.87 | DAO (0.36) | TSHRUSP30 | |
| SCHEMBL1234104 | 0.79 | NPSR1 (0.45) | TSHRUSP30 | |
| SCHEMBL1475922 | 0.76 | F2 (0.43) | USP30 | |
| SCHEMBL13053330 | 0.76 | HDAC3 (0.48) | TSHR | |
| SCHEMBL17599482 | 0.76 | USP30 (0.46) | TSHRUSP30 | |
| SCHEMBL12785064 | 0.74 | LMNA (0.41) | TSHRUSP30 | |
| SCHEMBL823673 | 0.74 | DAO (0.44) | USP30 | |
| SCHEMBL2786387 | 0.71 | KDM4E (0.43) | USP30 | |
| SCHEMBL23330402 | 0.69 | MEN1 (0.36) | USP30 | |
| SCHEMBL1372080 | 0.69 | NPSR1 (0.53) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888573-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125807-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |