Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823673 | 0.89 | DAO (0.44) | DAOPKMLIG1RXRARXRB | |
| SCHEMBL4959846 | 0.87 | TSHR (0.32) | USP30TSHR | |
| SCHEMBL363172 | 0.77 | DAO (0.50) | DAOPKMLIG1HPGDKMT2A | |
| SCHEMBL12785064 | 0.76 | LMNA (0.41) | HPGDUSP30P4HBGLAL3MBTL1 | |
| SCHEMBL1234104 | 0.76 | NPSR1 (0.45) | HPGDUSP30GLAL3MBTL1TSHR | |
| SCHEMBL1475922 | 0.75 | F2 (0.43) | USP30P4HB | |
| SCHEMBL30018730 | 0.73 | HPGD (0.48) | HPGDUSP30P4HBKMT2AL3MBTL1 | |
| SCHEMBL2786387 | 0.73 | KDM4E (0.43) | PKMHPGDUSP30GLAKMT2A | |
| SCHEMBL120211 | 0.70 | LPL (0.42) | USP30 | |
| SCHEMBL4150063 | 0.70 | DAO (0.41) | DAOPKMLIG1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888573-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125807-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |