Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110197 | 0.89 | PGR (0.45) | AR | |
| SCHEMBL4959670 | 0.86 | MRGPRX4 (0.39) | AR | |
| SCHEMBL4959655 | 0.86 | MRGPRX4 (0.39) | AR | |
| SCHEMBL4106028 | 0.83 | AR (0.46) | AR | |
| SCHEMBL4959617 | 0.81 | PGR (0.50) | — | |
| SCHEMBL4962255 | 0.77 | MRGPRX4 (0.40) | AR | |
| SCHEMBL4960690 | 0.77 | PGR (0.35) | — | |
| SCHEMBL4112533 | 0.76 | PGR (0.48) | AR | |
| SCHEMBL4106340 | 0.75 | PGR (0.47) | AR | |
| SCHEMBL4103189 | 0.72 | PGR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874732-A1 | PYRAZOLE DERIVATIVES AS PROGESTERONE RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111856-A1 | PYRAZOLE DERIVATIVES AS PROGESTERONE RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 2006-10-26 | — | — | WO | disclosed |