Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962335 | 0.89 | NR4A2 (0.47) | NR4A2RAB9AALDH1A1HPGDCYP2C19 | |
| Phenethylamine SCHEMBL4962587 | 0.88 | RAB9A (0.47) | NR4A2NPC1RAB9AALDH1A1CYP2C19 | |
| SCHEMBL4960277 | 0.81 | MEN1 (0.39) | NPC1RAB9AALDH1A1HPGDCASP3 | |
| SCHEMBL31121938 | 0.75 | ACHE (0.44) | L3MBTL1TDP1ACHE | |
| SCHEMBL24171989 | 0.75 | ACHE (0.44) | L3MBTL1TDP1ACHE | |
| SCHEMBL24171986 | 0.74 | ACHE (0.43) | L3MBTL1TDP1ACHE | |
| SCHEMBL31121940 | 0.74 | ACHE (0.43) | L3MBTL1TDP1ACHE | |
| SCHEMBL24171802 | 0.74 | ACHE (0.43) | ALDH1A1TDP1ACHE | |
| SCHEMBL14621794 | 0.74 | ACHE (0.43) | NPC1RAB9AL3MBTL1TDP1ACHE | |
| Phenethylamine SCHEMBL6778632 | 0.74 | CYP2C19 (0.44) | NPC1RAB9AALDH1A1CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401816-B1 | PROCESS FOR THE PRODUCTION OF THE PIPERIDINE DERIVATIVE FEXOFENADINE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-7235665-B2 | Process for the production of piperidine derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-20040198983-A1 | Process for the production of piperidine derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| US-6743941-B2 | INCLUDING FEXOFENADINE, USING THE CLAIMED CHEMICAL INTERMEDIATE, P-(2-CARBOXYETHYLCARBONYL)-ALPHA,ALPHA-DIMETHYLPHENYLACETIC ACID, ALKYL ESTER | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-01 | — | — | US | disclosed |
| EP-1401816-A1 | PROCESS FOR THE PRODUCTION OF THE PIPERIDINE DERIVATIVE FEXOFENADINE | Aventis Pharma Deutschland GmbH (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030105329-A1 | Process for the production of piperidine derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-06-05 | — | — | US | disclosed |
| WO-2002102776-A1 | PROCESS FOR THE PRODUCTION OF THE PIPERIDINE DERIVATIVE FEXOFENADINE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105329-A1 | Process for the production of piperidine derivatives | HRH2, HRH1, HRH4 | NR4A2 1967/4885NPC1 3730/4885RAB9A 1695/4885 |
| US-20040198983-A1 | Process for the production of piperidine derivatives | HRH2, HRH1, HRH4 | NR4A2 1967/4885NPC1 3730/4885RAB9A 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.