Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 5/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 5/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 4/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL4962587 | 0.81 | RAB9A (0.47) | CYP2C19POLBGAABRS3SMN1; SMN2 | |
| SCHEMBL15522680 | 0.80 | BRS3 (0.51) | POLBBRS3ALDH1A1MAPTESRRG | |
| SCHEMBL23583035 | 0.79 | NR1H4 (0.54) | BRS3ALDH1A1FFAR1 | |
| SCHEMBL23582506 | 0.77 | BRS3 (0.51) | CYP2C19POLBGAABRS3SMN1; SMN2 | |
| SCHEMBL5364970 | 0.74 | LOXL2 (0.53) | BRS3SMN1; SMN2LOXL2KMT2AKDM4E | |
| Phenethylamine SCHEMBL4960273 | 0.74 | NR4A2 (0.40) | CYP2C19GAALOXL2ALDH1A1CYP1A2 | |
| SCHEMBL28758271 | 0.72 | BRS3 (0.54) | BRS3SMN1; SMN2KMT2AMAPTESRRG | |
| SCHEMBL3656294 | 0.72 | CYP4A11 (0.54) | POLBBRS3ALDH1A1ESRRG | |
| SCHEMBL23582934 | 0.72 | BRS3 (0.49) | CYP2C19POLBGAABRS3 | |
| SCHEMBL728471 | 0.72 | KCNN4 (0.67) | CYP2C19KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743941-B2 | INCLUDING FEXOFENADINE, USING THE CLAIMED CHEMICAL INTERMEDIATE, P-(2-CARBOXYETHYLCARBONYL)-ALPHA,ALPHA-DIMETHYLPHENYLACETIC ACID, ALKYL ESTER | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-01 | — | — | US | disclosed |