SCHEMBL4960481

SCHEMBL4960481

Oc1cc(F)ccc1N1CCN(c2ccc(F)cc2O)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
GAA P10253 2/20 0.47
HTT P42858 2/20 0.47
NOTUM Q6P988 1/20 0.40
AR P10275 1/20 0.39
MAPT P10636 1/20 0.38
GRM5 P41594 2/20 0.38
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
HPGD P15428 1/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7830360 0.87 KDR (0.50) DRD2DRD4HTR3A
Hydrochloric Acid SCHEMBL5987905 0.85 KDR (0.49) ALDH1A1GAAHTTMAPTDRD2
SCHEMBL5987669 0.85 TP53 (0.55) ALDH1A1L3MBTL1GAANOTUMMAPT
SCHEMBL17893752 0.80 NPC1 (0.48) ALDH1A1L3MBTL1GAAHTTAR
SCHEMBL14797371 0.75 ALDH1A1 (0.53) ALDH1A1L3MBTL1CA3CA6CA5A
SCHEMBL11567310 0.73 GAA (0.39) ALDH1A1GAAHTTMAPTDRD2
SCHEMBL14570983 0.71 KDR (0.50) DRD2DRD4HTR3A
SCHEMBL17770436 0.70 GAA (0.44) ALDH1A1GAAHTTMAPTDRD2
SCHEMBL25003072 0.70 CA3 (0.36) ALDH1A1L3MBTL1CA3CA6CA5A
SCHEMBL5715714 0.70 ALDH1A1 (0.61) ALDH1A1L3MBTL1GAAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1988108-B1 Temperature and pH-sensitive block copolymer having having excellent gel strength, method of preparing the same, and drug delivery system using the same UNIV SUNGKYUNKWAN FOUND (KR) 2014-09-10 EP claimed
US-20080274190-A1 TEMPERATURE AND pH - SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT GEL STRENGTH, METHOD OF PREPARING THE SAME, AND DRUG DELIVERY SYSTEM USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2008-11-06 US claimed
EP-1988108-A1 Temperature and pH-sensitive block copolymer having having excellent gel strength, method of preparing the same, and drug delivery system using the same Sungkyunkwan University Foundation for Corporate Collaboration (KR) 2008-11-05 EP claimed
EP-1988108-B1 Temperature and pH-sensitive block copolymer having having excellent gel strength, method of preparing the same, and drug delivery system using the same UNIV SUNGKYUNKWAN FOUND (KR) 2014-09-10 EP disclosed
US-8586087-B2 Temperature and pH-sensitive block copolymer having excellent gel strength SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2013-11-19 US disclosed
US-20080274190-A1 TEMPERATURE AND pH - SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT GEL STRENGTH, METHOD OF PREPARING THE SAME, AND DRUG DELIVERY SYSTEM USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2008-11-06 US disclosed
EP-1988108-A1 Temperature and pH-sensitive block copolymer having having excellent gel strength, method of preparing the same, and drug delivery system using the same Sungkyunkwan University Foundation for Corporate Collaboration (KR) 2008-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274190-A1 TEMPERATURE AND pH - SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT GEL STRENGTH, METHOD OF PREPARING THE SAME, AND DRUG DELIVERY SYSTEM USING THE SAME TBCA, HSPA1B, AHSA1 ALDH1A1 763/4885L3MBTL1 4410/4885CA3 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.