SCHEMBL25003072

SCHEMBL25003072

N=C1SCCN1c1ccc(F)cc1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
INMT O95050 2/20 0.32
HTR1A P08908 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
P2RX7 Q99572 2/20 0.32
HSD17B3 P37058 1/20 0.32
AR P10275 1/20 0.32
NOTUM Q6P988 1/20 0.32
NR1I2 O75469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25001894 0.77 GAA (0.38) ALDH1A1GAAHTTINMTNOTUM
SCHEMBL25003073 0.72 INMT (0.32) ALDH1A1INMTARNOTUMSMN1; SMN2
SCHEMBL25003074 0.70 MEN1 (0.47) ALDH1A1INMTHTR1ASLC6A2SLC6A4
SCHEMBL4960481 0.70 ALDH1A1 (0.50) CA3CA6CA5ACA9CA14
SCHEMBL25002137 0.69 INMT (0.32) INMT
SCHEMBL25003075 0.66 INMT (0.39) ALDH1A1GAAINMTMAPTKDM4E
SCHEMBL25002906 0.65 MEN1 (0.45) CA5ACA9CA14CA5BALDH1A1
SCHEMBL25002603 0.64 ALDH1A1 (0.46) ALDH1A1GAAHTTMAPTKDM4E
SCHEMBL25001900 0.64 ADRB1 (0.42) ALDH1A1GAAINMTP2RX7NOTUM
SCHEMBL7830360 0.64 KDR (0.50) HTR1ASLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023015156-A1 PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION HUDSPETH A JAMES (US) 2023-02-09 WO disclosed