Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960716 | 0.88 | HCRTR1 (0.46) | ABCB1KDM4EALDH1A1SMN1; SMN2HCRTR1 | |
| SCHEMBL4304614 | 0.84 | SPR (0.44) | ABCB1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4962995 | 0.79 | DAGLA (0.41) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4308699 | 0.76 | SPR (0.48) | ABCB1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4965210 | 0.75 | DAGLA (0.40) | ABCB1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4312614 | 0.73 | KMT2A (0.43) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4962541 | 0.73 | HRH3 (0.35) | KCNH2 | |
| SCHEMBL4316050 | 0.72 | SPR (0.45) | MEN1KMT2AKCNH2 | |
| SCHEMBL4304826 | 0.69 | MEN1 (0.48) | ABCB1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4962104 | 0.69 | HCRTR1 (0.35) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |