Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 11/20 | 0.41 |
| ▸ | DAGLB | Q8NCG7 | 8/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964653 | 0.89 | DRD4 (0.42) | DAGLADAGLBABHD6HSD11B1 | |
| SCHEMBL4965210 | 0.86 | DAGLA (0.40) | DAGLADAGLBABHD6KDM4EMEN1 | |
| SCHEMBL4304826 | 0.84 | MEN1 (0.48) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4960742 | 0.79 | ABCB1 (0.40) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4308023 | 0.77 | CCR3 (0.41) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4311700 | 0.76 | POLB (0.43) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4964327 | 0.75 | DRD4 (0.42) | DAGLADAGLBABHD6 | |
| SCHEMBL4308692 | 0.73 | DRD4 (0.52) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4962541 | 0.73 | HRH3 (0.35) | — | |
| SCHEMBL4965205 | 0.72 | DAGLA (0.41) | DAGLADAGLBABHD6HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |