Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282509 | 0.90 | ATM (0.46) | THRBTHRAALDH1A1GAARORC | |
| SCHEMBL282344 | 0.85 | THRB (0.59) | THRBTHRAALDH1A1GAARORC | |
| SCHEMBL18918559 | 0.85 | THRB (0.48) | THRBTHRARORC | |
| SCHEMBL8892263 | 0.84 | THRB (0.43) | THRBTHRARORCHTR2ASLC6A4 | |
| SCHEMBL18932877 | 0.82 | THRB (0.46) | THRBTHRAALDH1A1RORCHTR2A | |
| SCHEMBL8892137 | 0.82 | MAPT (0.43) | THRBTHRAALDH1A1GAARORC | |
| SCHEMBL8892393 | 0.80 | EGFR (0.43) | THRBTHRAALDH1A1RORCHTR2A | |
| SCHEMBL18932875 | 0.80 | THRB (0.55) | THRBTHRARORC | |
| SCHEMBL18998446 | 0.78 | THRB (0.40) | THRBTHRARORCHTR2ASLC6A4 | |
| SCHEMBL23863340 | 0.78 | THRB (0.45) | THRBTHRARORCHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890768-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128056-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |