Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 8/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496276 | 0.88 | UCHL1 (0.36) | UCHL1F10GPR119NR1H2NR1H3 | |
| SCHEMBL13780947 | 0.81 | F10 (0.61) | UCHL1F10 | |
| SCHEMBL3828770 | 0.81 | UCHL1 (0.46) | UCHL1F10GPR119NR1H2NR1H3 | |
| SCHEMBL3828779 | 0.81 | UCHL1 (0.44) | UCHL1F10 | |
| SCHEMBL4497009 | 0.79 | F10 (0.51) | F10 | |
| SCHEMBL4492699 | 0.78 | F10 (0.41) | F10SYK | |
| SCHEMBL4961883 | 0.77 | F10 (0.70) | F10 | |
| SCHEMBL3696448 | 0.77 | MEN1 (0.36) | F10GPR119NR1H2SYK | |
| SCHEMBL4598458 | 0.77 | F10 (0.35) | F10SYK | |
| SCHEMBL4599382 | 0.77 | HDAC8 (0.35) | F10SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194643-A1 | Factor Xa Inhibitor Crystalline Forms | PFZER INC | 2008-08-14 | — | — | US | disclosed |
| EP-1891044-A1 | CRYSTALLINE FORMS OF A KNOWN PYRROLIDINE FACTOR XA INHIBITOR | Warner-Lambert Company LLC (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006100565-A1 | CRYSTALLINE FORMS OF A KNOWN PYRROLIDINE FACTOR XA INHIBITOR | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194643-A1 | Factor Xa Inhibitor Crystalline Forms | F2, F12, F2R | UCHL1 4051/4885F10 17/4885PARP1 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.